Anoxia

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Causes:

There are many different events in childhood that can lead to anoxia, including:

  • submersion (e.g. near drowning)
  • cardiac and/or respiratory arrest
  • suffocation (e.g. acute asthmatic event; strangulation)
  • carbon monoxide or neurotoxic exposure (e.g. barbiturate)
  • events that damage the respiratory system (e.g. TBI; crushing injury)
  • intra-operative complications leading to cardiopulmonary arrest
  • perinatal injury
  • lightning, electrical injury, electrical shock

Some brain structures are more vulnerable to the effects of anoxia. These include:

  • hippocampus
  • thalamus
  • basal ganglia
  • cerebellum
  • borderline or "watershed" zones between the major arteries of the cortex

Diagrams: watershed -- lateral; watershed -- coronal

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